The Workshop explores issues, challenges and opportunities for addressing health equity and social determinants of health in the African Region. The work of WHO Regional Office in addressing key determinants is presented and interventions that have been supported are shared and discussed. The priority actions contained in the strategy for addressing key determinants of health in the African region are used to form the basis of the discussions. Health equity issues focusing on health financing and draws from experiences in the African region. Health financing is core component of health systems, and as such, many countries have implemented major reforms to health systems financing in the past decade or so, with a view of making health care more accessible and equitable to their population. However, households may encounter financial hardship and poverty as result of health spending through out-of-pocket payments (OOP). Finally, the context of global initiatives such as the WHO Commission on Social Determinants of Health (2008); the Rio Declaration (WHO, 2011) on Social Determinants of Health and the Adelaide Statement on Health in All Policies will also be discussed. Expected Outcomes: Participants will have the opportunity to: 1. Explore the concepts and approaches applied in addressing social determinants of health in the African Region to reduce the health equity gap. 2. Define principles, frameworks and tools for SDH e.g., Health in All Policies, good governance for health, community participation and partnerships action for health equity 3. Examine issues underpinning success or failure of universal coverage including access to health insurance, prepayment and tax-based systems, social health insurance systems or mixed systems that commonly exist in most developed countries that have reached universal coverage.