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Wednesday, April 29, 2009
Sadrivaan A and B (The Hilton Istanbul Hotel )
PRE-ECLAMPSIA AND LIPID PROFILE ABSTRACT Objectives: The present study was designed to evaluate the role of lipid profile alteration in the development of Pre-eclampsia. Methodology: We selected 32 pregnant women, 16 healthy pregnant women (mean age 25.56±3.68) as normal and 16 already diagnosed preeclamptic women (mean age 24.65±4.25) as study group. Serum lipid profile (total lipids, cholesterol, triglycerides, HDL-cholesterol and LDL- cholesterol) of thirty-two women with Pre-eclampsia (n=16), normotensive women (n=16) were monitored. Results: The serum triglyceride concentrations increased significantly (232.18±106.41 vs. 113.12 ±21.3, P<0.01) while Serum HDL-cholesterol concentrations decreased significantly (39.75±11.99 vs. 51.18±06.09, P<0.01) in preeclamptic group as compared to normal pregnant women. Conclusion: Lipid metabolism plays a key role in the pathophysiology of Pre-eclampsia. Increased triglycerides levels along with decreased HDL-cholesterol levels and delayed triglycerides clearance and high blood pressure are associated with development of preeclampsia. KEY WORDS: Preeclampsia, High Density Lipoproteins, Triglycerides, Low Density Lipoproteins.
Learning Objectives: To gain and achieve higher level of knowledge and proficiency in current techniques and their clinical application. To maintain the required high standards and quality and maintain up to date Knowledge and new techniques, and participate in research and development.
Sub-Theme: Public Health and Research: Evidence Based Policy on Health