Baseline Malaria Epidemiology and Normal References Ranges for Biological Parameters in Maferinyah, Guinea

Baseline malaria epidemiology and normal references ranges for biological parameters in Guinea
Beavogui AH, Djimde A, Diallo MM , Dicko A, Sagara I , Sylla MM , Togo A, Toure S, Camara  D , Diallo MS , Yattara M , Camara G , Sow A , Sylla M , Cisse A , Diawara EY, Niare O , Dao A , Doumbo OKD .
Background: The emergence and spread of malaria strains resistant to widely available antimalarial drugs have greatly crippled malaria control in endemic countries. The identification of new therapeutic /prevention tools and the development of local skills remain a public health priority.
Objective: To determine the normal references values for biological parameters and measure the age specific incidence disease among children and adults during the two consecutive years
Methods: This is an observational study (two cross sectional surveys) to determine the burden of malaria among the participants from 3 months to 45 years.
Results: Overall 465 subjects were included and blood has been collected in April and August 2011. The third Blood collection is schedule on March 2012. Preliminary results show that the malaria infection rate at the beginning of the transmission is nearly 33 percent. Plasmodium falciparum was the most frequent parasite found in our study site (94 percent). The association of Plasmodium falciparum and Plasmodium malariae was respectively about 3.3 percent and 6.5 percent in the first and the second surveys. The mean values and median of the haematological and biochemical parameters were within the limits of international references. Nevertheless, the final values will be calculated after the three surveys.
Conclusion: Although our results are preliminary, they indicate that the Plasmodium falciparum is the predominant species in our sample and justify the direction of control strategies towards this species.
Key words: Plasmodium falciparum, haematological, biochemical and Guinea.